Ethical regulations and limited paediatric participants are key challenges that contribute to a median delay of 6 years in paediatric mAb approval.To overcome these barriers, modelling and simulation methodologies have been adopted to design optimized paediatric clinical studies and reduce patient burden.The classical modelling approach in paediatr
Key Factors Affecting the Deformation and Failure of Surrounding Rock Masses in Large-Scale Underground Powerhouses
The stability of the surrounding rock masses of underground powerhouses is always emphasized during the construction period.With the general trends toward large-scale, complex geological conditions and the rapid construction progress of underground powerhouses, deformation and failure issues of the surrounding rock mass can emerge, putting the safe
Localization and tissue tropism of the symbiont Microsporidia MB in the germ line and somatic tissues of Anopheles arabiensis
ABSTRACTThe Anopheles symbiont, Microsporidia MB, is maternally inherited and has a strong malaria transmission-blocking phenotype in Anopheles arabiensis.Microsporidia MB is also vertically transmitted, sexually transmitted, and avirulent.These characteristics are expected to promote its spread through mosquito populations, enhancing the potential
Smart Wheelchair Controlled Through a Vision-Based Autonomous System
People are preoccupied with their own duties in Hockey Skates - Orthotics today’s environment, making it tough to oversee and care for disabled people.Paralyzed and disabled people, on the other hand, have a powerful desire to move around freely.Different initiatives have been taken in the past to improve and preserve the self-esteem of such